Erythropoietic protoporphyria and x-linked protoporphyria. Protoporphyrin IX: the Good, the Bad, and the Ugly. The prevalence of argyria is unknown. You can prevent argyria by limiting your use of medications that contain silver and avoiding dietary supplements that contain silver. Itchy and flaking skin are potential side effects of this illness. This skin discoloration is also known as cyanosis. He acquired the disorder by drinking a home-made brew that included colloidal silver and using a silver-based salve on his face. There are no ads set to this area or maximum limit of ads on a single page has been reached They will be cleaned and protected from further contamination. Here's how to watch. Erythropoietic protoporphyria and x-linked protoporphyria. This will usually go away on its own. Cyanotic congenital heart disease (CCHD) is a condition present at birth. What causes the condition, and what symptoms will your child experience. It has also been found in people on specific medications., Since there is no cure for fish scale disease, treatment options are designed to help cope with and manage the disease. Treatments include:. In their case, blue skin was caused by a rare genetic disease called methemoglobinemia. The most common symptom of the condition is breakouts that appear pimple-like. In methemoglobinemia, the hemoglobin is unable to carry oxygen and it also makes it difficult for unaffected hemoglobin to release oxygen effectively to body tissues. Some experts believe that it could be linked to genetics, issues within the immune function, and hormones. From there, the family members married each other, and the genes were passed down from one inbred generation to the next, making the blue family locally famous. Peeling Feet: Symptoms, Causes, and Treatment, Hidradenitis Suppurativa (Acne Inversa) Overview, The Connection Between Hidradenitis Suppurativa and PCOS. It is not clear what causes this increase in elastin in people with this condition.. There are three broad groups of occupational skin disease: Irritant contact dermatitis. The cause for the condition is relatively unknown. segregation. Skin Disorders Several skin disorders are also exacerbated by anxiety. It might not be as serious as you think. 2005 - 2023 WebMD LLC. Extinct giant tortoise was the 'mammoth' of Madagascar 1,000 years ago. The exact cause of IGD is unknown, but this condition has been associated with other autoimmune diseases. [9], Benjamin Stacy, born in 1975, was the last known descendant of the Fugates to have been born exhibiting the characteristic blue color of the disorder, though he quickly lost his blue skin tone, exhibiting only blue tinges on his lips and fingertips when he became cold or agitated.[5]. Melanoma is a type of skin cancer that can spread to other organs in the body. 2019;81(1):91-101. doi:10.1016/j.jaad.2019.02.068. Keep the immune system healthy through good diet and sleep habits, not smoking, and frequent handwashing. Milk, cottage cheese, yogurt, wholegrain cereals, leafy green vegetables, egg whites, meat, kidney, and liver can all help you get in your daily quota. Cyanosis can also suggest theres something wrong with areas of the body, such as the: Most often, cyanosis is a symptom of a serious health condition. In James Camerons 2009 blockbuster "Avatar," the forest-loving Navi have stunning blue skin. Blue skin is also an emergency if: In some cases, even though emergency treatment isn't necessary, you may need medical evaluation and treatment. Blue skin can be caused due to insufficient blood flow or oxygen, medications, skin conditions (birthmarks/moles) or bruising due to an injury. (2018). A reference to "the Huntsville subgroup" is made in the American version of television sitcom Shameless when Kevin Ball (played by Steve Howey) discovers that he may have ancestors from that group. Pregnant or nursing women should not take spirulina or any dietary supplement without speaking to their doctor first. conditions of autosomal recessive. Although the majority of cases are mild and present with dry, dead skin cell accumulation in one specific area of the body, some more severe cases can cover larger spaces. In this therapy, you will receive oxygen through a mask or a tube placed in your nose. Learn about the top nine causes of fatigue and associated fatigue symptoms. The Occupational Safety and Health Administration (OSHA) and the Mine Safety and Health Administration (MSHA) enforce a limit of 0.01 mg/m3 for metallic and soluble silver compounds. For conditions that affect your heart or blood vessels, your doctor may prescribe medications, surgery, or other treatments. A severe asthma attack makes it incredibly hard to breathe and is a medical emergency. Many conditions can cause your skin to have a bluish tint. Sores heal slowly, and when they heal, they turn into a dark spot. 13. This condition results from extended amounts of contact with silver compounds or the ingestion of silver salts. Adults can also develop the condition if they have cancer, kidney failure, or thyroid disease. Clinical, epidemiologic, histopathologic and molecular features of an unexplained dermopathy. PROMPTLY CONSULT YOUR PHYSICIAN OR CALL 911 IF YOU BELIEVE YOU HAVE A MEDICAL EMERGENCY. Such as waking up frequently during the night. This occurs due to a decreased amount of hemoglobin in the baby's blood. Taking medication or using products that contain silver may cause blue skin. Oxygen-rich blood is deep red and causes your skins normal color. 2016;356(2):267-75. doi:10.1124/jpet.115.228130. Occasionally, peeling may also occur on the arms and legs. Blue skin can be caused due to insufficient blood flow or oxygen, medications, skin conditions (birthmarks/moles) or bruising due to an injury. In this case the hands turn white, then blue, then red. "Severe/life-threatening allergic reaction skin one sign along with anaphylaxis progressive, cause unknown. [8] His findings were published in the Archives of Internal Medicine in 1964. [5] He treated the family with methylene blue, which eased their symptoms and reduced the blue coloring of their skin. All content of this newsletter is intended for general information purposes only and is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Individuals who have this disease are at risk of developing very dark, almost chocolate- colored blood or blue skin. Wear more layers and warmer clothes during wintertime. Pictures and symptoms of the red, scaly rash. Afamelanotide has been reported to be effective for EPP. The chances of developing or being born with acral peeling skin syndrome are incredibly rare at less than one in a million. Sometimes lips that change color may be a warning sign. The disease is not life-threatening, but the discoloration of the skin can pose challenges in day-to-day life. Exposure to silver can take place through occupational exposure like workers involved in silver mining, taking medications with silver salts such as eye drops, using colloidal silver supplements like those for arthritis and diabetes, and during certain surgical and dental procedures involving silver sutures and silver dental fillings. Acquired cases are more likely to occur and are usually the result of exposure to certain medications or chemicals such as nitrates, silver or benzocaine. Using a 5% hydroquinone treatment on your skin may curb the amount of silver in your skin and make it look better. Visit our corporate site (opens in new tab). The Blue Fugates of Troublesome Creek was an entire family from Eastern Kentucky made up of blue-skinned people. Garg A, Kirby JS, Lavian J, Lin G, Strunk A. Sex- and Age-Adjusted Population Analysis of Prevalence Estimates for Hidradenitis Suppurativa in the United States. Flu shots help, too, by preventing another illness from taking hold. Narrowband UVBphototherapy increasesmelanincontent in the skin and induces skin thickening so to provide some level of protection from the sun. Oral antioxidants such as beta-carotene,Polypodium leucotomas extract, warfarin, and N-acetyl cysteine have been used, but are not supported by evidence. J Am Acad Dermatol. Erythropoietic protoporphyria (EPP) is a skin disorder caused by genetic mutations that cause a deficiency of enzyme protoporphyrin IX. It's unclear what the exact cause of this skin disorder is. All possible ___________ of chromosomes are in the gametes produced by meiosis. As a result, four of their seven children exhibited blue skin, and continued reproduction within the limited local gene pool ensured that many descendants of the Fugates were born with met-H.[3][4][5], The disorder can cause heart abnormalities and seizures if the amount of methemoglobin in the blood exceeds 20 percent, but at levels between 10 and 20 percent it can cause blue skin without other symptoms. The Cure Clin Cosmet Investig Dermatol. Dry skin symptoms cause the skin to become scaly, rough & flaky. Acral peeling skin syndrome is a genetic skin disorders that lead to the painless peeling of the top layer of skin. If you're experiencing blue skin, it's also likely to experience: Start a chat with Buoy AI assistant to find out whats causing your blue skin. 2015;37(7):577-80. doi:10.1097/DAD.0000000000000146, Wouters CH, Maes A, Foley KP, Bertin J, Rose CD. This creates a long-lasting tan. It can arise early or late in life and may come and go or be present all the time, depending on the cause. Blue skin symptoms Blue skin is an unwelcome development, to say the least, whether it's all over the body or restricted to the hands, face, or a particular skin bump. It may only affect one area of skin, or it could change the appearance of all your skin. Aspiration Pneumonia occurs when food, saliva, liquids, or vomit is breathed into the lungs or airways leading to the lungs, causing an infection. This is caused by capillaries in the face dilating, which allow in more blood and can make the skin of the face noticeably red. In some conditions, blue skin occurs because the blood is carrying an abnormally low amount of oxygen. Blood that has lost its oxygen is dark bluish-red. Infection - eg, candida, dermatophytes, pseudomonas, herpes simplex. People with autoimmune disorders should also avoid spirulina as it can stimulate the immune system. DermNet NZ. National Center for Advancing Translational Science. Verywell Health's content is for informational and educational purposes only. Some causes of cyanosis are difficult to prevent. Rare green comet not seen since the Stone Age will zoom overhead tonight. This pet nail clipper with LED light allows your dog or cat to easily enjoy the manicure process! Eye Drop Usage. Etiology and evaluation of cyanosis in children. 14. Morgellons can cause a wide variety of symptoms, including:. Anti-Inflammatory Diets May Improve Fertility, Exercise May Be an Anti-COVID Secret Weapon, Dr. Whyte's Book: Take Control of Your Diabetes Risk, Street Medicine Reaches People Where They Live, Health News and Information, Delivered to Your Inbox, Silver nitrate used to treat gum bleeding and, Silver acetate used in lozenges and other products to help, Colloidal silver protein used in eyedrops. The person will, however, become a carrier, and it can still be passed down to future children. Yes, it turns out, and a family living in Appalachia had the condition for generations. This is because of a condition called methemoglobinemia, which causes methemoglobin levels in the red blood cells to rise above 1 percent.It turns the skin blue, the lips purple, and the blood a . Cold fingers or toes. inheritance. Pneumonia is often contracted in hospitals or nursing homes. "Some lung and heart diseases can cause the fingernails . Blisters can appear suddenly and spread, and can linger for years. Those suffering from Central Cyanosis will usually have Peripheral Cyanosis, which is a bluish or purple discoloration of the fingers and toes. It can also arise in patients with kidney disease who have an impaired ability to produce NADH. Treatment involves treating or eliminating the cause. Prevalence and incidence of rare diseases: Bibliographic data. Heterozygotes are affected. The most famous case history of methemoglobinemia comes from six generations of the Fugate family, who lived in isolation in the hills of Kentucky from 1800 to 1960. National Organization for Rare Disorders. You might get argyria if you take dietary supplements that contain silver, use medication such as eyedrops or nose sprays that contain silver, or work where silver particles are in the air. Bronchiectasis is destruction and widening of the large airways. Angelica Bottaro is a professional freelance writer with over 5 years of experience. If your hands turned blue after exposure to the cold, you may have a condition called Raynauds phenomenon. Levels of melanin depend on race and amount of sunlight exposure. 1064nm Q-switched Nd:YAG laser for the treatment of Argyria: a systematic review, History of Morgellons disease: from delusion to definition, Unexplained Dermopathy Study Team. Top Symptoms: dry cough, shortness of breath, fingers looking plump, Symptoms that always occur with interstitial lung disease: dry cough. 5 These may irritate active eczema, Apply lotions and creams to damp skin to trap in the moisture (within three minutes of showering/bathing), Lotionand creams can be kept underocclusionfor one or two hours with a cling-film wrap to enhance skin hydration, Gently rub a pumice stone on wet skin to help remove thickened crusty skin, Brush washedhairto removescalesfrom scalp, A lack of recoil of the skin, or the skin tissues inability to take on its original shape after being deformed, Increase sensitivity to sound, taste, smell, or touch (hyperesthesia), Red or skin-coloured patches,papules,andplaques, Lesions wax and wane, and may vary in size and shape over days to months, The lesions tend to be symmetrically distributed on the trunk, butproximallimbs may also be affected, A history of autoimmune diseases, such asmyasthenia gravis,systemic lupus erythematosus, or thymoma, Regular use of certain medications: Chelating agents, such as penicillamine, ACE inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, antibiotics, such as penicillin, anti-seizure medications, such as phenobarbital, and thiols, Pustules,fluctuantpseudocysts, and abscesses, Draining sinuses linking inflammatorylesions, Family history of hidradenitis suppurativa, Obesity andinsulinresistance (metabolicsyndrome), Inflammatory bowel disease, particularly Crohn's disease, Other skin disorders, includingpsoriasis,acne,hirsutism, Comorbidities like hypertension, diabetes mellitus,dyslipidaemia, thyroid disorders,arthropathies,polycystic ovary syndrome, adverse cardiovascular outcomes, Syndromes like PAPA syndrome, PASH syndrome, and PAPASH syndrome, Pain medications, both over the counter and prescription strength, Hair that can be plucked easier than what is typical. By clicking Accept All Cookies, you agree to the storing of cookies on your device to enhance site navigation, analyze site usage, and assist in our marketing efforts. Waardenburg syndrome is a group of genetic conditions that can cause hearing loss and changes in coloring (pigmentation) of the hair, skin, and eyes. Cyanosis occurs when there's too little oxygen in the blood. Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Top Symptoms: fatigue, cough, headache, loss of appetite, shortness of breath, Symptoms that always occur with bacterial pneumonia: cough. 2013;88(3):413-6. doi:10.1590/abd1806-4841.20131864, Griffith RD, Simmons BJ, Bray FN, Falto-Aizpurua LA, Yazdani Abyaneh MA, Nouri K. 1064nm Q-switched Nd:YAG laser for the treatment of Argyria: a systematic review. All rights reserved. 2005-2023 Healthline Media a Red Ventures Company. The wounds are treated similarly to severeburns. Blue skin is an unwelcome development, to say the least, whether it's all over the body or restricted to the hands, face, or a particular skin bump. It occurs when a person comes into contact with excessive amounts of silver, and it can affect either the whole body . Certain skin conditions may have a bluish appearance. The Blue Fugates were famously known for inheriting and passing on the rare gene that causes methemoglobinemia, a blood disorder that produces an abnormally high amount of methemoglobin (a form of hemoglobin). Some people's internal organs in their abdomen -- such as the spleen, liver, and intestines -- take on a bluish color, but you wouldnt know this unless you had surgery. 2018;11:71-90. doi:10.2147/CCID.S152343, Pearson ML, Selby JV, Katz KA, Cantrell V, Braden CR, Parise ME, Paddock CD, Lewin-Smith MR, Kalasinsky VF, Goldstein FC, Hightower AW, Papier A, Lewis B, Motipara S, Eberhard ML; Unexplained Dermopathy Study Team. This dietary supplement can cause argyria. It is usually present at birth, but can appear later in childhood or in early adulthood. Blue skin often means there's an issue with the flow of your blood or oxygen supply. Aside from being a beautiful shade of bluish-green, spirulina boasts an exciting amount of health benefits. When ingested, silver gathers in the skin and other organs and does not dissipate. Melanogenesis is the name of the process where melanins are produced by specialized pigment cells called melanocytes, in response to UV radiation. U.S. National Library of Medicine: MedlinePlus. In very rare instances, EPP has been reported to have been caused by myelodysplasia ormyeloidleukaemia.. Laser therapy has also been explored as a viable option for the treatment of the disease. A very superficial injury causes a reddish bruise, but in a slightly deeper injury the leaked blood appears to be blue in color. Makeup can help hide the effects of argyria on your skin. They may also order one or more tests, such as: In blood tests, extremely low concentrations of hemoglobin can cause cyanosis. Learn about diagnosis, treatment. There is no cure for EPP, so treatment is usually focused on symptom control. Ichthyosis vulgaris: Who Gets and Causes. Cyanosis in infants and children. It seems like a no-brainer, but it's more complex than that. doi:10.5070/D3202021540, American Academy of Dermatology Association. The biggest risk factor is genetic mutations of specific genes such as the ferrochelatase gene or the delta-aminolaevulinic acid synthase-2 gene. These mutations are inherited. One or both eyes may have a bluish sclera, and it's usually not painful. Typically, the amount of pigment change in the skin depends on the level of silver in the body, and it can take a long time for symptoms to show. Textbook of pediatric emergency medicine. Dry skin, also known as xerosis or xeroderma, has many causes, including cold or dry weather, sun damage, harsh soaps, and overbathing. J Am Acad Dermatol. The following uses of silver are among those that have been shown to cause argyria: On the job. conditions of autosomal dominant. The Fugates, a family living in the hills of Kentucky starting in the 19th century, were commonly known as the "Blue Fugates"[1] or the "Blue People of Kentucky". Carriers may have bluish lips and fingernails at birth, which usually lighten. There have been rare cases of argyria caused by silver-coated acupuncture needles, silver earrings, and dental pieces. This makes us very distressed, so we need to trim our pet's nails frequently. Over the years, the skin on the backs of the hands and cheeks can have some thickening with subtle pitted scarring.. Potential side effects of argyria on your skin and make it look better and,! Concentrations of hemoglobin in the blood oxygen supply of sunlight exposure they turn into a dark spot carriers have.:577-80. doi:10.1097/DAD.0000000000000146, Wouters CH, Maes a, Foley KP, Bertin J Rose! The Bad, and it can still be passed down to future children James! Bad, and it & # x27 ; s nails frequently may prescribe medications, surgery, or it be... With LED light allows your dog or cat to easily enjoy the manicure process also avoid spirulina as can... Itchy and flaking skin are potential side effects of this illness potential what causes blue skin disorder effects of this illness 'mammoth of... Deficiency of enzyme protoporphyrin IX skin and make it look better progressive, cause.... There & # x27 ; s an issue with the flow of blood! Be linked to genetics, issues within the immune system cause blue skin was caused by silver-coated needles... You have a bluish or purple discoloration of the large airways, including peer-reviewed studies, to support the within! It seems like a no-brainer, but the discoloration of the top layer skin. Backs of the top nine causes of fatigue and associated fatigue symptoms keep the immune system healthy Good! Is destruction and widening of the hands turn white, then red through a or., which eased their symptoms and reduced the blue coloring of their skin the blood it incredibly hard breathe! Type of skin it can also develop the condition if they have,! There are three broad groups of occupational skin disease: Irritant contact dermatitis to and. Forest-Loving Navi have stunning blue skin and symptoms of the red, scaly rash a decreased amount sunlight. Purposes only have an impaired ability to produce NADH was an entire family from Eastern Kentucky made up blue-skinned. Other autoimmune diseases manicure process s more complex than that disorders should also avoid spirulina as it can the. He acquired the disorder by drinking a home-made brew that included colloidal silver and using 5! Prevent argyria by limiting your use of medications that contain silver may cause blue skin occurs the! A type of skin an abnormally low amount of silver, and it can stimulate the immune,! Mutations that cause a deficiency of enzyme protoporphyrin IX occurs due to a decreased amount of Health.! Can spread to other organs in the Archives of Internal Medicine in 1964 with flow! The forest-loving Navi have stunning blue skin was caused by a rare genetic disease methemoglobinemia! Also occur on the backs of the large airways in Appalachia had the condition is breakouts that appear.. Ability to produce NADH is breakouts that appear pimple-like shade of bluish-green, boasts. He acquired the disorder by drinking a home-made brew that included colloidal silver and using a 5 % hydroquinone on..., Foley KP, Bertin J, Rose CD, or other.... Nine causes of fatigue and associated fatigue symptoms a decreased amount of hemoglobin cause... Blue, then red J, Rose CD Kentucky made up of blue-skinned people in. Melanins are produced by specialized pigment cells called melanocytes, in response to UV.. That appear pimple-like acral peeling skin syndrome is a type of skin, or other treatments can linger for.... Heal, they turn into a dark spot should not take spirulina any! Effects of argyria caused by genetic mutations that cause a deficiency of enzyme protoporphyrin IX widening of the large.... Into a dark spot 911 if you believe you have a bluish tint a person comes into contact with amounts! May curb the amount of oxygen our corporate site ( opens in tab... Uvbphototherapy increasesmelanincontent in the gametes produced by specialized pigment cells called melanocytes, in response UV... Then blue, then red the cold, you may have a condition present at birth, which eased symptoms. Blood appears to be effective for EPP linked to genetics, issues within immune. Preventing another illness from taking hold acid synthase-2 gene are at risk of developing very,. S usually not painful may prescribe medications, surgery, or other treatments the! Subtle pitted scarring or purple discoloration of the red, scaly rash 5 ] he the... Can also develop the condition is breakouts that appear pimple-like placed in your skin and make look... From Eastern Kentucky made up of blue-skinned people from Eastern Kentucky made up of blue-skinned people is! Ability to produce NADH for what causes blue skin disorder on symptom control hands turned blue after to... Or in early adulthood which eased their symptoms and reduced the blue coloring of their skin name the! Then red of symptoms, including: also occur on the backs of the hands turn white, then.... Have an impaired ability to produce what causes blue skin disorder tortoise was the 'mammoth ' of Madagascar years! The backs of the top layer of skin sunlight exposure disorder caused by a rare genetic called... Uv radiation groups of occupational skin disease: Irritant contact dermatitis to other organs and does not dissipate 'mammoth! 'S content is for informational and educational purposes only % hydroquinone treatment on your skin and skin... Synthase-2 gene oxygen is dark bluish-red and does not dissipate fingers and.. And flaking skin are potential side effects of argyria caused by genetic mutations of specific genes as. Incidence of rare diseases: Bibliographic data but can appear later in or... Concentrations of hemoglobin can cause the fingernails cause blue skin was caused by silver-coated acupuncture needles, earrings! That have been shown to cause argyria: on the cause the most common symptom of large... A medical emergency dark spot ingestion of silver salts also develop the condition and... Or it could change what causes blue skin disorder appearance of all your skin or blue skin often means there & # x27 s... Contracted in hospitals or nursing homes dietary supplement without speaking to their doctor first s too little in! ; Severe/life-threatening allergic reaction skin one sign along with anaphylaxis progressive, cause.. The fingers and toes when they heal, they turn into a dark spot with subtle pitted scarring gametes by! Less than one in a slightly deeper injury the leaked blood appears to be blue in.. Exacerbated by anxiety or thyroid disease, candida, dermatophytes, pseudomonas herpes... 1,000 years ago too little oxygen in the blood and causes your skins normal color symptoms the! Bibliographic data is the name of the fingers and toes become a carrier, and hormones breakouts... Failure, or it could change the appearance of all your skin the! To other organs and does not dissipate prevent argyria by limiting your use of medications contain! Deep red and causes your skins normal color, histopathologic and molecular of... Increasesmelanincontent in the body made up of blue-skinned people developing or being born with acral peeling skin syndrome is professional! A bluish or purple discoloration of the hands turn white, then blue, which eased their symptoms reduced. Skin to become scaly, rough & flaky being born with acral skin!, become a carrier, and when they heal, they turn into a spot... Response to UV radiation exciting amount of oxygen a million avoiding dietary supplements contain! A beautiful shade of bluish-green, spirulina boasts an exciting amount of salts... Disease: Irritant contact dermatitis, epidemiologic, histopathologic and molecular features of an unexplained dermopathy surgery or! And when they heal, they turn into a dark spot may curb the of! The time, depending on the backs of the hands turn white, then blue, which eased their and! Depending on the arms and legs will zoom overhead tonight Madagascar 1,000 years.... Or other treatments a genetic skin disorders that lead to the cold what causes blue skin disorder may. Skin one sign along with anaphylaxis progressive, cause unknown pet & # x27 ; s issue. By meiosis treatment is usually focused on symptom control skin are potential side effects of argyria your! Of sunlight exposure in James Camerons 2009 blockbuster `` Avatar, '' the forest-loving Navi stunning... Smoking, and the Ugly ( EPP ) is a condition present at birth Medicine in 1964 passed to... Is genetic mutations of specific genes such as: in blood tests, as... ; 37 ( 7 ):577-80. doi:10.1097/DAD.0000000000000146, Wouters CH, Maes a Foley. Is usually present at birth Archives of Internal Medicine in 1964 he treated family! Means there & # x27 ; s an issue with the flow of your blood or oxygen supply extremely! Also arise in patients with kidney disease who have an impaired ability produce. Both eyes may have a condition present at birth, but the discoloration of the hands and can... Acral peeling skin syndrome are incredibly rare at less than one in million. Down to future children a deficiency of enzyme protoporphyrin IX: the Good, skin... Bibliographic data such as: in blood tests, such as: in blood tests, such as ferrochelatase. Bluish tint birth, but the discoloration of the condition is breakouts that appear.! ; some lung and heart diseases can cause the skin can pose challenges in day-to-day life ingestion silver... Cat to easily enjoy the manicure process produced by specialized pigment cells called melanocytes in. And flaking skin are potential side effects of this illness born with acral peeling skin syndrome are incredibly at! Bluish-Green, spirulina boasts an exciting amount of hemoglobin in the baby & # x27 ; s an with... Breathe and is a skin disorder is IX: the Good, the Bad and.
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what causes blue skin disorder